I've used them for LR target shooting and LR deer hunting.
I"ve done limited shooting with the .257" 115g VLD out of my 25-06, one load at 3025fps, the other at 3260fps. They are both very accurate loads. I haven't gotten a chance to shoot any animals with these, yet. I have however shot milk jugs with them at 400 yards and it all but desintegrates the milk jugs. So my initial thought is they are going to be very destructive bullets, good for coyotes, maybe antelope, but I dont know if I'd trust them on deer based on what I"ve seen with VLD's from my 7 RM.
The ones I"ve used for hunting (muleys) were the 168g and 180g VLD out of a 7 RM at 2950fps and 2825fps from my 24" rem 700. Very accurate bullets. I've got 3 recorded kills with the 168g vld and 1 kill with the 180g vld. Both bullets couldn't have acted more differently IMO. Shot a coyote about 75 yards in the neck with the 168g vld and it left about a 2-3" exit hole, coyote was DRT. 1st deer kill was a buck I my buddy shot around 250 yards with the 168g VLD at 2950fps. He hit him behind the shoulder as he is a meat hunter. At the shot, you could instantly see blood coming out the exit hole like old faithful. The buck went up the hill about 5 yards then back down about 20. There was about a 2" exit hole and massive internal damage. Perfect IMO. Few days later I was able to fill my tag at 618 yards. I dialed in and held for the shoulder. At the shot the buck dropped and started rolling downhill, however he was clearly not dead, but not able to get up. I put another one in his neck and that settled it. Upon arriving, I noticed no exit on the 1st initial shoulder hit. On the 2nd and killing neck shot, the bullet exited but I found a small chunk of the bullet right on the edge of the exit hole. When I skinned it out, the 1st bullet had hit the shoulder bone and went about 3/4 of the way through. The insides were completely torn apart. I never did find the bullet, just pieces of the jacket. After those 2 experiences I decided I'd play with the heavier 180g for the next year.
Next year came and I had my chance with the 180g VLD at 2825fps. I figured the 125fps difference in speed/weight should give me a little better penetration and not so much expansion. Few days into the season I shot a forked horn about 100 yards was all, straight on the shoulder, the little buck just stood there and barely made a flinch. I put another one behind his shoulder and he ran off a little ways and eventually fell over dead. Upon examininng/skinning the deer, the bullets just didn't open up at all. I had very little internal damage and PINSIZE exit holes on both shots.
I also shot milk jugs filled with water with both 168 and 180 VLD's and they both had the same effect on deer as the jugs IMO. With the 168's they all but desintegrated the jugs, obviously showing violent expansion. With the 180's, they were falling over like if you had shot them with FMJ's. No "POP" what-so-ever.
I decided to not use VLD's out of my 7 RM at least for deer hunting. I didn't want to risk the bullet not doing its job, even though I did mine.
I have also played with the .308" 210g VLD out of a 300 RUM at 3000fps. I shot LR targets out to 1150 yards with these and they did extremely well with a little tuned up factory 700 BDL. The only animal I shot with the 210g VLD was a very unlucky coyote at about 100 yards. Hit him in the shoulder and a poof of hair blew out about 10 yards in diamter and flipped the coyote backwards. It left about a pie plate exit and he was basically hanging by the top and bottom skin. From that perspective, I'd say those bullets were also showing very rapid expansion, even on such a small thin skinned animal.
My conclusion is that I probly wont be using Bergers VLD's on anything I want to put on my wall. I just dont trust them. There are other bullets out there that will shoot almost just as far, but give you the same terminal perfermance near 100% of the time instead of sometimes.
They are very accurate bullets and great for LR target shooting. I"d also use them for coyotes as I dont save pelts.
Best I can say is try them out in whatever you got. If you have good experience with them and they are working for you, then great!!