I`ve used H414,IMR4895,Varget,and IMR4064.
Currently using 38gr of IMR4064 topped with a 75gr VMax.Same load shot very well in a friends rifle also.
All were very good.If you plan on loading for another caliber pick a powder that applies to both.
For using bullets from 55gr to 100gr H414 would be a good pick for a 243Win alone.But too slow for .223 Remington for example.The same could be said for either of the 4350`s.
However..either 4895`s,Varget,or 4064 fits the bill nicely for lots of calibers.The above load devastated my first coyote and heaps of groundhogs.