Unfortunately, the majority of my coyote hunting will be in a shotgun-only deer hunting area, and my only rifle deer hunting is an over-.224 caliber area, so the .22-250, or even a .220 Swift barreled with a 1-8 twist (should give almost identical velocities to the new .22 Creedmoor with 80 grain bullets, right?) is out of the running as a potential crossover caliber.
Quote:Im kind of in your shoes in looking for a good crossover round, but im not set on the pre ww2 period. By your title i would go with a fast twist 22-250 so you could shoot heavy .22 bullets, but if deer are going to be somewhat regular thing i would go with the 257 bob. The 243 was brought up, and (arguably) the 257 is going to give a bit better results (velocity, energy) than the 243 on deer. If the coyote pelts dont matter to you, definitely the 257. If so, 22-250 imo.
I have occasional access to a .222 Remington from a family member, and I don't have a trapping license, so the only time I'd want coyote pelts might be one or two to hang on the wall of my college kid apartment or to line a wool blanket with, and in that case I have a better rifle for that use, than the 'heavy' rifle I'm looking at with the .257 Bob/.220 Swift area of calibers.