Originally Posted By: DirtpoodleI am going to try some 52 grain Sierra HPBT Match for deer, I have heard that they work very well when the velocity is high. I have never shot a deer with one, if anyone has first hand knowledge, any info and loads would be apreciated. Make sure that Sierra bullet is a hunting Bullet and not just a "MATCH" grade bullet. Most Match grade bullets even though they are hollow points are not designed for expansion like a hunting bullet. The hollow point is a simple means of displacing weight to allow for a extremly well balanced flat shooting paper puncher. Now with that said My dad has been shooting whitetails with his 22-250 for years with a old 60gr solid base Noslers. I have even taken two with my .204 with 45gr. Hornady spire points.(sold the .270 and was only option at the time) We've had great results with both, but like with anything it all boils down to shot placement. These aren't brush guns, and that is another thing you must think about when about to pull the trigger.