I've killed several, the 55g Hornady Sp is a really good bullet, tough and very accurate. Also, the Sierra 63g Seimi point will stabalize in a 1-14 twist and is extremely accurate.
The 60g Nosler partition with about 39.0g of IMR 4350 with a win primer will group 1 1/2" in a 1-14 twists that I have shot(700's). The nosler partition is the mack daddy of the 22 bullets for deer, they are not however a target grade bullets that will achieve tiny groups...not necessary for deer.
I shot two does with a 223 loaded with 26.5g of 748 with a 55g Rem Hp, they dropped right on the spot, lung shots.
My brother killed half a dozen deer last year with a 223 and the 53g Tripple shock, one at 270 yards.
As usual, it is not about caliber so much as it is about shot placement.
PO Ackley wrote much about how fast the 220 Swift killed deer with a 45g Sp. I believe most of his shots were head and neck shots. His ultimate confidence of how accurate his rifle was lead him to make some really great shots with the Swift.
The 63g Sierra Semi point in a Swift is a great deer round as long as you pick your shots and angles.
For a guy that gets very excited when he sees deer, I would not recommend a 22 caliber of any kind to that that guy(my dad). My dad got very excited and every buck he saw was a Hartford kind of deer that would score 120-180. He was just as apt to hit them in the butt as shoot an antler off, we did lots of tracking for him. No amount of practice got him out of getting so excited all his life, we thought he was going to have a heart attack on several occasions, barely able to talk...he has gone on to be with the Lord now.
If you are prone to get excited, then opt for a 30 caliber with a 150g Hornady Sp or a 7 Mag with a 160g Sierra BTSP that will leave a HUGE blood trail.