BrentWin, years ago I shot a max load of IMR 4350 with the 60g Sierra hp, the bullet did not open up on yotes unless you hit a rib or a sholder. I remember shooting a kit fox with it and it put a nickel size hole in it.
The problem with shooting a bullet this tough is that you may loose animals. I did try and shoot FMJ in the early 80's, but lost a lot of animals...I got them, but I did not get them.
I have had great luck with the Accuracy loads that are listed in the Nolser manual. Not all of their accuracy loads are the loads that my rifle likes, but it is surprising how often the accuracy load for my gun ends up being within 1.0g of what the Nosler book says.
You may want to check the Nosler manual for some of their minimum loads that they say is the most accurate for that bullet. Just substitute for a less explosive bullet of the same weight.