If you intend to use those bullets I would approach that as if I were bowhunting. Restrict yourself to good angles and stay away from bone. A head on shot won't leave a pin drop of blood on the ground if the deer runs off. The lightest bullet I shoot deer with in the .243 Winchester/6mm Remington is 85 gr. There are so many good bullets in the caliber that I don't need to use anything that is possibly going to leave me with a bad result.
I agree. If you are hunting private property where you know you will get numerous opportunities you can be selective and pick your shot angle. I hunt public land in Oregon and often need to take advantage of a single opportunity that presents itself and the perfect shot angle might not be available. For that reason I like the following in my 243s:
Savage 243: 90g Nosler AB for deer, 90g Nosler BT for coyote. On this particular rifle both bullets shoot to virtually the same place on the paper which means I do not need to adjust my scope between bullets.
Tikka 243: - 85g Barnes TSX for deer. I also have loaded the 85g Nosler Partition and it shoots good, but not quite as tight of a group.
I have found that Ramshot Hunter gives good accuracy and good velocity on all these bullets, but other powders such as Varget, I4350, I4064, and H414 all work too. Hard to find a powder that doesn't work in the 80g-90g class for the 243. I am currently using I4350 in my Savage and the Ramshot in my Tikka.
Gosh I love the 243. I reload for several other cartridges ranging from the 222 Rem all the way up to the 300 Win Mag, but for me the 243 is an obsession. Some day I would like to have a 6mm Rem barrel built. I have dreamed of owning one for years. I just need to think of a way to convince my wife that I need another gun. lol