First off I think using a 100 gr in 243 wastes most of the potential of a 243.
That said IMR 8208 XBR Is for smaller bullets, like a 55gr. It will make a rocket, 4000 fps.
In my 6mm Remington, I get over 4200 fps.
Try Superformance and an 80 or 85 gr bullet and look out...