"...100 grain .243 round will slam a coyoye, oviously, but it was a complete pass through the boiler room with suprisingly little exit damage."
This is what generally happens when a 100 grain .243 fails to drop a deer.
While it really depends on where the bullet hits the deer, velocity at impact has EVERYTHING to do with how well--or even if--the bullet will expand.
The folks who own the farm next to where I hunt all use .243's, and believe it or not--they all use the Nosler 70 grain (seventy grain) Ballistic Tip. And they've been very successful at dropping deer with that bullet, launched at what is likely an average 3250 fps. They have stuck with that load (45 grains of IMR 4350 and the 70 grain BT) because it has worked. I wouldn't have thought to use that, but I can't argue with sucess.
Deer really aren't that hard to kill.
My brother has used the 100 grain factory Winchester and Remington .243 stuff on deer--and has reported at least three failures to kill with what appeared to be good hits--and these were very likely pass thru shots where the heavier, slower bullet did not encounter enough resistance to open up and dump its energy in the deer's vitals. He uses a .308 now, but others whom he hunts with who do use .243's have typically gravitated toward the 80 grain weight class of bullets. From the guys who actually use .243's on deer, you'll find a preponderance of recommendations for lighter bullets. They appear to have learned this by trying both the 100's and the 80's.
Me? I just use my "thutty-thutty" as Jack O'Conner once called it. So far, no run-offs... /ubbthreads/images/graemlins/grin.gif
Dan