Smokes them! I've used the 60 gr. Partition in my standard .223 16" AR15 on a half dozen deer. Mostly bucks, a couple that would field dress about 160 lbs. Shot through the heart/lungs from under 100 yards not one has ran over 60 yards. From memory most of those exited the off side. The Barnes TSX 62 gr. works as well.
Every normal man must be tempted, at times, to spit on his hands, hoist the black flag, and begin slitting throats.