Smokes them! I've used the 60 gr. Partition in my standard .223 16" AR15 on a half dozen deer. Mostly bucks, a couple that would field dress about 160 lbs. Shot through the heart/lungs from under 100 yards not one has ran over 60 yards. From memory most of those exited the off side. The Barnes TSX 62 gr. works as well.
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Every normal man must be tempted, at times, to spit on his hands, hoist the black flag, and begin slitting throats.