I am shooting them in a 22 Creedmoor, and have been for a couple of years now. Over a stiff charge of Varget, they are bad medicine for anything I point them at. I think I am up to 5 deer, countless coyotes, and a a sack full of pigs.
The regular old 69 MK kills coyotes and pigs just fine, the TMK just shoots a little better, especially once you get out past 500 or so.