My neighbor and I reload right at the rifle range, we have a heated and AC house to load and shoot from.
Changing primers on a load is very, very revealing to say the least. Primer choice can make a huge difference if you are looking for small groups. Weird thing is that it is more often than not, hard to predict what will work the best or give the smallest SD.
You can see a big difference between a Winchester primer and a CCI 200, again with the fed 215, and again with a Win mag primer.
9 1/2, CCI 200 will often give similar results, then a Fed 210 is a softer flame and will show another change.
Putting up a chronograph while you are changing primers is a reality check to say the least, as some primers may show HUGE extreme spreads, some with very low spreads, and some primers just will simply blow the group altogether.
If you have the mind set that you are going to use just one primer, you are deaf, mute, and blind.
Of course, if you are just looking for 1 1/2" groups, or shooting a rifle that has been through the Indian Wars, primers are not that important.