The 22 Nosler had such a rough start that it may never recover, but after trying 2 different barrels and having put hundreds of rounds down range I can say that the 22 Nosler has met all my expectations. Once the horrible AR Stoner barrel was tossed and replaced with a 20" White Oak barrel things made a 180 turn. I get exceptional accuracy with bullets from 40 to 69 grains. I also get the advertised velocity gains over .223 and when pushed hard it is close on the heels of 22-250 velocities. I currently have 3 hunting loads worked up for my rifle. 65 Sierra loaded in my old experimental Hagar brass at 3240 fps using RL-15 it is a warm load that has no ill effects on my brass. Next a 55 Nosler BT loaded with CFE-223 at over 3600 fps in Nosler brass, this is a max load that will only allow the brass to be loaded a few times. Lastly a 40 Nosler BT loaded with Alliant 1200-R at 3920 fps in Nosler brass, hot but not really hurting anything. These loads are for hunting coyotes so if the brass only lasts once it is ok, as I will likely loose a few pieces in the field anyway. Of course hand loads can be made that have no ill affects on the Nosler brass while still giving very good velocities.
The 55 grain factory ammo measured 3550 fps in my barrel and shot sub MOA, so there is also a viable factory offering. It is loaded with Winchester primers, and 33.5 grains of ball powder that is unidentifiable. CFE-223 shows 33.0 grains max in Noslers load data. It is the only ball powder near the same charge weight, but they do not fill cases to the same volume, so copying the factory load identically did not work out.
All in all with a good barrel this cartridge is a winner in my book, and worth a look for those wanting a speedy accurate cartridge in an AR platform.
