With IMR 4350 and a 150 grain bullet, in my testing, it didn't get good until 59.0 which is the listed max in the Nosler manual. Hodgdon list 58.0 as max with the IMR-4350. So work up. Another good powder with the 150's is IMR-4895. I would also try H4350, but the charges will be slightly different from the IMR version, as they share the same number, but are slightly different burn rate.
As far as 190 grain bullets your IMR-4350 will work there as well. Some others I would try are W760, and RL19.