The .257 Weatherby mag will easily take deer sized game to 600 yards. To be able to hit, reasonably well at that distance, would require a scope with turrets, and the knowledge and experience to run them. A good 3x9 would work, but most would go bigger. The biggest problem with the non-reloading shooter with a Weatherby, is cost of factory ammo, $60 a box. Shooting at a live animal at that range, is a growing trend, that I have mixed feelings about, but that's another can of worms.