Winchester white box 22-250

45 gr HP is just fine. When I was shooting .223 I shot the 45 gr winchester hollow points and I had very few get away. Shot placement is more important than grain of bullet.
 
I never had good luck with them on fox or coyote they left a huge exit everytime i used them changed to a 55 grain v-max and never had trouble after that. just my observation
 
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