Under the duress of an attack, robbery, or defending someone else, emotions of the moment having been caught off guard completely, may complicate issues as taking off a safety for use or cocking the hammer on the pistol. A safety or having to cock a hammer may just get you killed. It takes training and lot of practice to form a habit with little thought involved.
Often, bad guys will assault a person with zero warning, when they do, it seems an eternitity for you to get a Pistol out of your pocket or waist band, especially if one of them has his hands on you or you have been knocked half unconscious and are trying to regain your composure.
No hammer or safeties for me.
My brother in law was a Detective with the LAPD. He told me that the Smith J Frame snub nose was the hardest pistol to train officers to shoot accurately. I had the Smith custom shop do a trigger job on my J frame 2" and my accuracy from the draw was greatly improved...that is an understatement.
In the IDPA matches that I attend, the women seem to have a heck of a time manipulating the slide on some auto's, clearing jams, and strong trigger pulls.
There is a spring kit for the Ruger LCP that makes it a dream trigger. I have seen a great number of the Ruger LCP's and none of them I would say were inaccurate, however they do have their preference on ammo that shoots the most accurate.
I shoot the Buffalo Bore 90g HP at 1170 fps out of my Lcp.