Looking back at some old reloading notes, looked like I got up to 20.5 of IMR-4198 with the Sierra 52 HPBT in my 222 rem, using Rem 7 1/2 BR primers and seated at 2.125" COL. Be careful though and work up to this load because my notes say that 20.4 was the published "max load" for this combo at the time.
20.0 of IMR-4198 with a 50 Speer TNT (and Rem 7 1/2's at 2.125" again) was another excellent load. 20.0 was max load at the time as I recall, and rated at about 3,257fps.
50 Sierra BK's right at book max was another good one.
(I couldn't get 50 V-MAX's to group worth a darn over 3,000.)
My favorite though, and the one I'm shooting currently is:
21.0 of IMR-4198
Hornady 40gr V-MAX bullet
CCI 400 Small Rifle Primers
2.130" COL
3,300 fps out of an old '79 Rem700 BDL
(using Hornady brass, where I had a bunch of this saved up from days of buying Hornady Custom Ammo 50gr V-MAX Moly's).
I tried lots of other powders... BL-C2, H335, etc., but always came back to IMR-4198 for the 222.