25/06's are not hard to load for. I shot out the barrels in three varmint rifles in the 80's shooting 100g Sierra's and 90g sierra BTHP with IMR 4350, from 51.5-53.0g in win cases.
With today's powders, you can get a lot more velocity with accuracy with R#19 with the 100's with win primers, my rifle loves 57g at 3400 fps and the speer 100g BTSP is a 1 1/2" group at 300 yards with a 6-24 Pentax on the rifle, win brass only.
I also had great luck with the 100g Hornady flat base with 57.0g of R#25 with a fed 215 primer in win case, and the 115g Sierra BTSP with R#25 also. R#25 gave me extremely low standard deviations in speed.
Work up to these loads in your rifle, my lot# of powder and barrel is probably very different than yours.
One technique that is great for the 25/06 is the use of a Forester neck sizing die that will bump the shoulders back after firing the case. The 25/06 loves loads that are on the warm side for the rifle and full length sizing at the best accruacy load is common. If you bump the shoulder back with this Forester neck sizer, you will not have to neck size for 8+ firings, which means that you are also not over working your brass nor trimming your brass very often.
Here is a good site that lists loads by shooters themselves in their particular rifle:http://www.centerfirecentral.com/viewer.html