We can use anything we want here at night and I use a 22 magnum semi auto. In fact I have three, two 10-22mags and a Voquartsen. I like and use the follow up shot capability all the time, but...I am not blasting the animals first with a light. I have two Night Vision weapon sights and one Thermal scope. As above, you might not have much of an advantage with a semi if you have to shine the animal with a light.