52g Sierra BTHP, 53g Sierra HP, 50g Sierra Sp, ALL sierra 55g bullet weights work especially well on coyotes including shooting through shoulders and hip joints, they also do not blow up on the spine.
If you are stuck on a 55g poly tip bullet, the 55g Nosler ballistic tip is a whale of a bullet on coyotes.
I did a lot of bullet testing on Mexican Coyotes in a 22/250, only bullet I had trouble with was a 52g Speer hp at 3800, they blew up on the shoulders an ribs. Even the Sierra 45g High Velocity Sp worked extremely well on coyotes out of a 22/250.
I personally choose a bullet of tougher construction due to the fact that quartering shots demand a bullet of tougher construction. The 55g Hornady Sp with the cannalure is a very accurate bullet and much tougher than it's poly tip counter parts.
Bottom line, stuff is not hard to kill, you just have to hit them in the right place.