The great thing about the Grendel is the wide weight range of bullets. For 120 and 130 gr bullets, blc2 and TAC are powders that I've had good luck with. 2520 works real well too, but I have trouble finding it locally. For lighter bullets, I like H335 and X-terminator. Benchmark is another powder that works. The brass I've used the most is AA/Lapua Grendel brass or fire formed 7.62x39 (Lapua and Win.) With fire formed x39 brass, you have to remember that it holds on average 2 grains less than Grendel brass AFTER it's fire formed, so max loads for x39 brass needs to be 94% of published loads. The x39 brass is just thicker, so the case capacity is less.
The following are all using AA/Lapua brass and CCI 450 primers. The groups were all sub MOA with the 100 NBT being the best at 1/2 MOA. I know I could fine tune each load and get even better results, but I get bored sitting at a bench. Once I get a sub MOA group, I'm done. I have been told that Hornady brass uses the same load info as Lapua, but I can't confirm this yet.
120 SMK
28.4 gr TAC
100 NBT
29.8 gr X-Terminator
(it's .1 gr over Ramshot's max but shoots REALLY good in my rifle)
95 V-Max
30.0 gr. H335
The bullets I want to try, but being unemployed is hampering my testing, is the 100 gr Lapua BTHP and the 100 gr. Berger BTHP. They are supposed to be really good.
Basically, with the Grendel, the closer to max load you get, the better your groups are, but don't go over too much, or you'll start breaking lugs off your bolt.
EDIT: Oh yeah, this works in my rifle, use at your own risk, start low and work up....insert lawyer CYA babble here...