seen alot of deer droped at 200+ yrds, w/ hot hanloaded 55 g bal tip nosler, some of them perfect placement, some a little off, still did in, i personaly hit 1 at 370 through the neck and out the shoulder w 22-250, you think no way, my experince has been at a o -80 yrd range first sign of bone bal tips are gonna blow up, once the velocities tame a little(longer yrds) the bullet has a good bit of penetration, i swear by nosler bal. tips in any cal. until they prove me wrong...
223-55g
22-250-55g
243-70g
25-06-100g
30-378-165g