Duckboat, I can't answer your question on temperature, I can not remember the last time I took more than one shot at a deer.
I shoot a load of 65g of R#22; CCI 250, with a 160g Sierra BTSP, 162g A-Max, and 162g SST. Every Rem 700 that I have ever owned shot the 71-72g of R#22, CCI250, with the 120 Nosler Ballistics into very tiny groups. I aim to try some 120g Barnes Tripple shocks when my supply of 120g NOslers run out, I will back off on my load that I shoot with the cup and core bullets and work upwards in powder charge.
A friend of mine shoots a load of 68g of R#22, CCI250 with the 140g Nosler ballistic tip and the 139g Hornady flat base with amazing accuracy.
Please exercise caution and work up to these loads in your rifle...lot# of powder can vary as much as 5%.
I have noticed that the R#22 seems to shine with CCI 250 primers vs other primers.
Good luck!